Since 2017, I have worked as a Research Biostatistician in the Department of Epidemiology and Biostatistics at Memorial Sloan Kettering Cancer Center. Below are a few highlights from research programs that I have been a part of, as well as related publications and presentations.
American Association for Cancer Research (AACR) project GENIE BPC (Genomics Evidence Neoplasia Information Exchange Biopharma Collaborative) is a cross-institution collaboration between MSKCC, Dana Farber Cancer Institute and Vanderbilt-Ingram Cancer Center with biopharmaceutical partners working towards linking cancer genomic sequencing data with clinical treatment and outcomes data (press release). As a part of the Statistical Coordinating Center, I am involved in writing standard operating procedures for quality assurance, maintaining a quality assurance dashboard, deriving variables that will be publicly released with the data and performing statistical analyses.
Related Publications
Lavery JA, Brown S, Curry MA, et al. A Data Processing Pipeline for the AACR Project GENIE Biopharma Collaborative Data with the {genieBPC} R Package. Bioinformatics (2023)
Choudhury NJ, Lavery JA, Brown S, et al. The GENIE BPC NSCLC Cohort: A Real-World Repository Integrating Standardized Clinical and Genomic Data for 1,846 Patients with Non-Small Cell Lung Cancer. Clinical Cancer Research (2023)
Lavery JA, Lepisto E, Brown S, et al. A Scalable
Quality Assurance Process for Curating Oncology Electronic Health
Records: The Project GENIE Biopharma Collaborative Approach. JCO
Clinical Cancer Informatics (2022)
Brown S, Lavery JA, Shen R, et al. Implications
of Selection Bias Due to Delayed Study Entry in Clinical Genomic
Studies. JAMA Oncology (2021)
Kehl KL, Riely GJ, Lepisto EM, et al. Correlation Between Surrogate End Points and Overall Survival in a Multi-institutional Clinicogenomic Cohort of Patients With Non–Small Cell Lung or Colorectal Cancer. JAMA Network Open (2021)
Related Presentations
In collaboration with the Exercise Oncology service at MSK, I have been a part of a number of protocols and research projects investigating the role of exercise in preventing cancer and improving survival among people with cancer. Select publications are highlighted below:
Lavery JA, Boutros PC, Scott JM, Tammela T, Moskowitz CS, Jones LW. Pan-Cancer Analysis of Postdiagnosis Exercise and Mortality. Journal of Clinical Oncology (2023)
Michalski M, Rowed K, Lavery JA, et al Validity of Estimated Cardiorespiratory Fitness in Patients With Primary Breast Cancer Journal of the American College of Cardiology: CardioOncology (2022)
Bliss, JW, Lavery, JA, Underwood, WP, Chun, SS, Fickera, GA, Lee, CP, Corcoran, S, Maloy, MA, Polubriaginof, FC, Kelly, DW and Scott, JM Impact of Exercise on Susceptibility and Severity of COVID-19 in Patients with Cancer: A Retrospective Study Cancer Epidemiology, Biomarkers & Prevention (2022)